Functionalisation of Carbon–Fluorine Bonds with Main Group Reagents
نویسندگان
چکیده
منابع مشابه
One-pot double functionalisation of π-deficient heterocyclic lithium reagents.
Herein, we report an efficient method for the double functionalisation of lithiated halogenopyridines, -pyrazines or -furopyridines through a convenient one-pot electrophilic trapping/nucleophilic substitution sequence.
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Porphyrins carrying either a primary alcohol, a tertiary alcohol or a primary bromide linker group were allowed to react with the surface silanol groups on silicate glass thermally at 80-240 °C to obtain a monolayer film. The kinetics of the reaction was analysed based on the pseudo-second order equation. The tertiary alcohol and the primary bromide reacted much slower than the primary alcohol....
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We report the regiospecific, rhodium-catalyzed borylation of saturated terminal C-H bonds in molecules with existing functionality. Moderate to good yields were obtained with the organic substrate in excess and as limiting reagent. The borylations of trialkylamines, protected alcohols, protected ketones, and fluoroalkanes occurred regiospecifically at the methyl group that is least sterically h...
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Over the past decade, mechanochemistry has emerged as a powerful methodology in the search for sustainable alternatives to conventional solvent-based synthetic routes. Mechanochemistry has already been successfully applied to the synthesis of active pharmaceutical ingredients (APIs), organic compounds, metal oxides, coordination compounds and organometallic complexes. In the main group arena, e...
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ژورنال
عنوان ژورنال: Synthesis
سال: 2016
ISSN: 0039-7881,1437-210X
DOI: 10.1055/s-0036-1588663